|
KMID : 0882420070730001003
|
|
Korean Journal of Medicine
2007 Volume.73 No. 0 p.1003 ~ p.1007
|
|
|
A case of alpha heavy-chain renal amyloidosis associated with multiple myeloma
|
|
Jun Yoon-Hee
Bae Seo-Eun
Ryu Jung-Hwa
Ryu Dong-Ryeol
Sung Sun-Hee
Hong Ki-Sook
Lee Soon-Nam
|
|
|
Abstract
|
|
|
|
Amyloidosis is a disease characterized by the extracellular deposition of amyloid in various tissues and organs, especially the kidney and heart. In patients with multiple myeloma, many factors contribute to the development of renal impairment including hypercalcemia, recurrent infections and the infiltration of myeloma cells as well as glomerular deposits of amyloid. We treated a case of alpha heavy-chain renal amyloidosis in a 54 year-old woman. The patient was admitted with generalized edema for 10 days, and was known to have the nephrotic syndrome. Renal biopsy was undertaken and the diagnosis of renal amyloidosis was made. Although she did not have bony lesions, anemia and hypercalcemia, the results of the serum and urine protein electrophoresis showed an M-peak, and multiple myeloma was confirmed by a bone marrow biopsy. We report herein a very rare case of alpha heavy-chain amyloidosis associated with multiple myeloma and review the medical literature.(Korean J Med 73:S1003-S1007, 2007)
|
|
|
KEYWORD
|
|
|
Amyloidosis, Alpha heavy-chain, Multiple myeloma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|